SOHO Flordis International, an Indonesian/Australian supplement and pharmaceutical company, is bringing a fat-finding dietary supplement to market in North America under the Calorease brand name. It promises to do what Olestra could not, that is, cut absorbed calories by husbanding undigested fat molecules through the intestinal tract without nasty side effects. The supplement is based on a fiber molecule, alpha-cyclodextrin, branded as FBCx (fat binding complex), first discovered and developed by researchers at Wayne State University in Detroit, MI. The fiber, a six glucose unit molecule, has unique fat binding properties. “It’s derived from grain. The actual structure of this molecule is unique in that allows the fiber to form a stable, non-digestible complex with dietary fat,” according to Jeff McHarg, managing director for North America for SOHO Flordis.
FBCx, on the other hand, forms a stable, bound unit with fat molecules, McHarg said. The intestinal tract interprets this complex much as it would any other undigestable plant fiber such as cellulose. Other fibers do this as well, but FBCx exhibits a game-changing difference. “Two grams of FBCx per fat-containing meal translates to a healthy weight loss of about 5 pounds a month,” he said. A two month, double-blind, placebo controlled study with FBCx showed statistically significant reduction of weight, total cholesterol, and LDL-cholesterol levels and increased insulin sensitivity. And animal and in vitro studies showed that rats exposed to alpha-cyclodextrin (FBCx) in the active group weighed less and had lower body fat content. FBCx was also shown to significantly reduce tricyglycerides and leptin, while increasing insulin sensitivity and fecal fat excretion.